ENG monoclonal antibody, clone 3A9
产品名称: ENG monoclonal antibody, clone 3A9
英文名称: ENG monoclonal antibody, clone 3A9
产品编号: MAB10524
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant ENG.
- Immunogen:
- Recombinant protein corresponding to human ENG.
- Host:
- Mouse
- Theoretical MW (kDa):
- 71
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In ascites (0.03% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis using ENG monoclonal antibody, clone 3A9 (Cat # MAB10524) against HEK293 (1) and CD105-hIgGFc transfected HEK293 (2) cell lysate.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human kidney cancer tissues (A) and stomach cancer tissues (B) using ENG monoclonal antibody, clone 3A9 (Cat # MAB10524) with DAB staining.
- Immunofluorescence
- Immunofluorescence analysis of HepG2 cells using ENG monoclonal antibody, clone 3A9 (Cat # MAB10524) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
- Entrez GeneID:
- 2022
- Gene Name:
- ENG
- Gene Alias:
- CD105,END,FLJ41744,HHT1,ORW,ORW1
- Gene Description:
- endoglin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD105 antigen,OTTHUMP00000022221,Osler-Rendu-Weber syndrome 1
- Related Disease
- Aneurysm
- Aneurysm, Ruptured
- Arteriovenous Malformations
- Cardiovascular Diseases
- Central Nervous System Vascular Malformations
- Chromosome Aberrations
- Diabetes Mellitus, Type 2
- Edema
- Epistaxis
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Hypertension, Pulmonary
- Intracranial Aneurysm
- Intracranial Arteriovenous Malformations
- Kidney Failure, Chronic
- Liver Cirrhosis
- Liver Diseases
- Lung Neoplasms
- Pre-Eclampsia