HMGCS2 purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： HMGCS2 purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： HMGCS2 purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00003158-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human HMGCS2 protein.
- Immunogen:
- HMGCS2 (NP_005509.1, 1 a.a. ~ 508 a.a) full-length human protein.
- Sequence:
- MQRLLTPVKRILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of HMGCS2 expression in transfected 293T cell line (H00003158-T02) by HMGCS2 MaxPab polyclonal antibody.
Lane 1: HMGCS2 transfected lysate(56.60 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 3158
- GeneBank Accession#:
- NM_005518.2
- Protein Accession#:
- NP_005509.1
- Gene Name:
- HMGCS2
- Gene Alias:
- -
- Gene Description:
- 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase (HMGCS2; EC 2.3.3.10) mediates the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for brain, heart, kidney, and other organs during times of carbohydrate deprivation such as fasting (Robinson and Williamson, 1980 [PubMed 6986618]). Also see cytoplasmic HMG-CoA synthase (HMGCS1; MIM 142940), which mediates an early step in cholesterol synthesis.[supplied by OMIM
- Other Designations:
- OTTHUMP00000013928,hydroxymethylglutaryl-CoA synthase 2
- Gene Pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Butanoate metabolism
- Metabolic pathways
- PPAR signaling pathway
- Synthesis and degradation of ketone bodies
- Terpenoid backbone biosynthesis
- Valine, leucine and isoleucine degradation
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Bipolar Disorder
- Cardiovascular Diseases
- Coronary Artery Disease
- Crohn Disease
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hypertension
- Kidney Failure, Chronic
- Lymphoma, Non-Hodgkin
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis