GPC3 polyclonal antibody
产品名称： GPC3 polyclonal antibody
英文名称： GPC3 polyclonal antibody
产品编号： PAB9896
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Sheep polyclonal antibody raised against partial recombinant GPC3.
- Immunogen:
- Recombinant protein corresponding to C-terminus of human GPC3.
- Host:
- Sheep
- Reactivity:
- Human
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Western Blot (5-10 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Value of glypican 3 immunostaining in the diagnosis of hepatocellular carcinoma on needle biopsy.
Anatelli F, Chuang ST, Yang XJ, Wang HL.Am J Clin Pathol. 2008 Aug;130(2):219-23.
- 2.
- Expression of glypican 3 in ovarian and extragonadal germ cell tumors.
Zynger DL, Everton MJ, Dimov ND, Chou PM, Yang XJ.Am J Clin Pathol. 2008 Aug;130(2):224-30.
- 3.
- Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR.Hepatology. 2008 Apr;47(4):1211-22.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 2719
- Gene Name:
- GPC3
- Gene Alias:
- DGSX,OCI-5,SDYS,SGB,SGBS,SGBS1
- Gene Description:
- glypican 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000024058,OTTHUMP00000062492,glypican proteoglycan 3