Anti-CXCR4 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106446P-50ul	solarbio	50ul	960.00元
K106446P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-CXCR4 Polyclonal Antibody
别名	CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	48kDa
Gene ID	7852
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human CXCR4
性状	液体
Public Immunogen Range	A synthetic peptide of human CXCR4
Subcellular Locations	Cell junction Cell membrane Early endosome Late endosome Lysosome Multi-pass membrane protein
Swiss Prot	P61073
克隆类型	Polyclonal Antibody
背景资料	Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.