PAK4 polyclonal antibody (A01)
产品名称： PAK4 polyclonal antibody (A01)
英文名称： PAK4 polyclonal antibody (A01)
产品编号： H00010298-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant PAK4.
- Immunogen:
- PAK4 (AAH02921, 68 a.a. ~ 157 a.a) partial recombinant protein with GST tag.
- Sequence:
- KTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEKPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLD
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.9 KDa) .
- MSDS:
Download
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 10298
- GeneBank Accession#:
- BC002921
- Protein Accession#:
- AAH02921
- Gene Name:
- PAK4
- Gene Alias:
- -
- Gene Description:
- p21 protein (Cdc42/Rac)-activated kinase 4
- Omim ID:
- 605451
- Gene Ontology:
- Hyperlink
- Gene Summary:
- PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- p21(CDKN1A)-activated kinase 4,p21-activated kinase 4,protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
- Related Disease