Anti-DDB1 Monoclonal Antibody-抗体-抗体-生物在线

Anti-DDB1 Monoclonal Antibody

商家询价

产品名称： Anti-DDB1 Monoclonal Antibody

英文名称： Anti-DDB1 Monoclonal Antibody

产品编号： K001425M

产品价格： null

产品产地：北京

品牌商标： solarbio

更新时间： 2025-01-16T13:35:33

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
邮编 : 101102
所在区域 : 北京
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产品详情

Anti-DDB1 Monoclonal Antibody
品牌：solarbio | 货号：K001425M
商品货号： 商品品牌： 规格 基本售价： 选择规格
K001425M-50ul solarbio 50ul 960.00元 
K001425M-100ul solarbio 100ul 1600.00元

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001425M-50ul	solarbio	50ul	960.00元
K001425M-100ul	solarbio	100ul	1600.00元

英文名称 Anti-DDB1 Monoclonal Antibody
别名 DDBA;UV-DDB1;XAP1;XPCE;XPE;XPE-BF
应用 WB
稀释比例 WB 1:1000.
交叉反应 Human Mouse Rat Monkey
蛋白分子量 127kDa
Gene ID 1642
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG2b
免疫原 Purified recombinant human DDB1 protein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human DDB1 protein fragments expressed in E.coli.
Subcellular Locations Cytoplasm Nucleus
Swiss Prot Q16531
克隆号 2D6-B5-E6
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit.This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage.Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas.However,it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit.In addition,Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.[provided by RefSeq,May 2012]

英文名称	Anti-DDB1 Monoclonal Antibody
别名	DDBA;UV-DDB1;XAP1;XPCE;XPE;XPE-BF
应用	WB
稀释比例	WB 1:1000.
交叉反应	Human Mouse Rat Monkey
蛋白分子量	127kDa
Gene ID	1642
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG2b
免疫原	Purified recombinant human DDB1 protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human DDB1 protein fragments expressed in E.coli.
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	Q16531
克隆号	2D6-B5-E6
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit.This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage.Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas.However,it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit.In addition,Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.[provided by RefSeq,May 2012]