Anti-HIF2alpha Polyclonal Antibody

品牌：solarbio | 货号：K106456P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106456P-50ul	solarbio	50ul	960.00元
K106456P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-HIF2alpha Polyclonal Antibody
别名 EPAS-1;HLF;Mhlf;HRF;Epas1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 65kDa
Gene ID 13819
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human HIF2alpha
性状 液体
Public Immunogen Range A synthetic peptide of human HIF2alpha
Subcellular Locations Nucleus
Swiss Prot P97481
克隆类型 Polyclonal Antibody
背景资料 Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD

英文名称	Anti-HIF2alpha Polyclonal Antibody
别名	EPAS-1;HLF;Mhlf;HRF;Epas1
应用	WB
稀释比例	WB 1:3000.
交叉反应	Human Mouse Rat
蛋白分子量	65kDa
Gene ID	13819
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	A synthetic peptide of human HIF2alpha
性状	液体
Public Immunogen Range	A synthetic peptide of human HIF2alpha
Subcellular Locations	Nucleus
Swiss Prot	P97481
克隆类型	Polyclonal Antibody
背景资料	Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD