SELPLG monoclonal antibody, clone KPL-1
产品名称： SELPLG monoclonal antibody, clone KPL-1
英文名称： SELPLG monoclonal antibody, clone KPL-1
产品编号： MAB7346
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against SELPLG.
- Immunogen:
- Full length human SELPLG.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- CD162 (KPL-1).
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.2 (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A novel P-selectin glycoprotein ligand-1 monoclonal antibody recognizes an epitope within the tyrosine sulfate motif of human PSGL-1 and blocks recognition of both P- and L-selectin.
Snapp KR, Ding H, Atkins K, Warnke R, Luscinskas FW, Kansas GS.Blood. 1998 Jan 1;91(1):154-64.
- Entrez GeneID:
- 6404
- Gene Name:
- SELPLG
- Gene Alias:
- CD162,CLA,PSGL-1,PSGL1
- Gene Description:
- selectin P ligand
- Omim ID:
- 600738
- Gene Ontology:
- Hyperlink
- Gene Summary:
- SELPLG is the high affinity counter-receptor for P-selectin on myeloid cells and stimulated T lymphocytes. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. The organization of the SELPG gene closely resembles that of CD43 and the human platelet glycoprotein GpIb-alpha both of which have an intron in the 5-prime-noncoding region, a long second exon containing the complete coding region, and TATA-less promoters. [provided by RefSeq
- Other Designations:
- cutaneous lymphocyte-associated associated antigen
- Gene Pathway
- Related Disease
- Antiphospholipid Syndrome
- Atherosclerosis
- Atherosclerosis
- Birth Weight
- Cardiovascular Diseases
- Cerebrovascular Accident
- Coronary Artery Disease
- Coronary Disease
- Coronary Restenosis
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hemorrhagic Disorders
- Inflammation
- Ischemia
- Leukemia
- Leukemia, Myeloid, Acute