Anti-GAPDH Monoclonal antibody
品牌：solarbio | 货号：K200057M

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K200057M-50ul
Solarbio
50ul
960.00元
K200057M-100ul
Solarbio
100ul
1600.00元
英文名称
Anti-GAPDH Monoclonal antibody
别名
GAPDH
应用
WB IHC IF
稀释比例
WB 1:3000-8000. IHC 1:100-300. IF 1:100-200.
交叉反应
H R M Mk Dg Ch Hm Rb Pg Sh Insect Yeast
蛋白分子量
36kDa
Gene ID
2597
保存
Store at -20°C. Avoid freeze / thaw cycles.
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法
Affinity purification
亚型
IgG1
免疫原
Recombinant protein of human GAPDH
性状
液体
Public 
Immunogen 
Range
Recombinant protein of human GAPDH
Subcellular 
Locations
Cytoskeleton Cytosol Nucleus
Swiss Prot
P04406
克隆类型
Monoclonal Antibody
背景资料
Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is 
well known as one of the key enzymes involved in 
glycolysis. As well as functioning as a glycolytic enzyme in 
cytoplasm, recent evidence suggests that mammalian 
GAPDH is also involved in a great number of intracellular 
proceses such as membrane fusion, microtubule 
bundling, phosphotransferase activity, nuclear RNA export, 
DNA replication, and DNA repair. During the last 
decade a lot of data appeared concerning the role of 
GAPDH in different pathologies including prostate cancer 
progression, programmed neuronal cell death, age 
related neuronal diseases, such as Alzheimer's and 
Huntington's disease. GAPDH is expressed in all cells. It is 
constitutively expressed in almost all tissues at high 
levels. There are however some physiological factors such 
as hypoxia and diabetes that increase GAPDH expression 
in certain cell types. GAPDH molecule is composed of four 
36kDa subunits.

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参考文献

《β-N-Oxalyl-L-α,β-diaminopropionic acid from Panax notoginseng plays a major role in the treatment of type 2 diabetic nephropathy》 作者:Li Jie,Qiu Pengcheng,Wang Siwang,WuJun sheng,He Qiaoyan,Li Kaifeng,Xu Lu 期刊:biomedicine & pharmacotherapy 影响因子:3.743 PMID:30928803