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上海信裕生物科技有限公司
TSP50抗体

TSP50抗体

商家询价

产品名称： TSP50抗体

英文名称： TSP50Antibody

产品编号： XY12574-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 TSP50抗体Applications

In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 1 citations –view here
Species specificity Human, Mouse; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 12574-1-AP;MCF7 cellMCF7 cells were subjected to SDS PAGE followed by western blot with 12574-1-AP(TSP50 antibody) at dilution of 1:300
  • 12574-1-AP;Ovary cancerImmunohistochemical of paraffin-embedded human ovary tumor using 12574-1-AP(TSP50 antibody) at dilution of 1:50 (under 10x lens)
  • 12574-1-AP;MCF-7 cellsImmunofluorescent analysis of MCF-7 cells using 12574-1-AP( TSP50 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Positive WB detected in MCF7 cells, HEK-293 cells, human testis tissue, mouse testis tissue
Positive IHC detected in Human ovary tumor tissue, human breast cancer tissue, human testis tissue
Positive IF detected in MCF-7 cells
Recommended dilution WB : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:10-1:100
 TSP50抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen TSP50 fusion protein ag3247 Full name Testes-specific protease 50
Calculated molecular
weight		 385aa,43 kDa Observed molecular 
weight		 50-55 kDa
GenBank accession 
number		 BC033016 Gene ID (NCBI) 29122
Gene symbol TSP50 Synonyms Cancer/testis antigen 20, CT20, PRSS50, Serine protease 50, testes protease 50, TSP50
Background TSP50抗体

TSP50 (Testis-specific protease-like protein 50) is also named as PRSS50, CT20 and belongs to the peptidase S1 family. It can enhance the expression of NFKB target genes involved in cell proliferation, and promotes cell proliferation, at least partially, through activation of the NFKB signalling pathway(PMID:21385156). There are two protein bands of 37 kDa and 43 kDa to be detected in human testes that the the difference is most likely caused by posttranslational proteolytic cleavage(PMID:11782390). The full length protein has a signal peptide with 39 amino acids and two glycosylation sites. TSP50抗体

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